4-methylumbelliferyl β-D-glucoside
4-methylumbelliferyl β-D-glucoside structure
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Common Name | 4-methylumbelliferyl β-D-glucoside | ||
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| CAS Number | 18997-57-4 | Molecular Weight | 338.309 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 626.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C16H18O8 | Melting Point | 258-263ºC (dec.) | |
| MSDS | USA | Flash Point | 233.9±25.0 °C | |
Use of 4-methylumbelliferyl β-D-glucoside4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2]. |
Summary: 4-Methylumbelliferyl-β-D-glucopyranoside (4-methylumbelliferyl β-D-glucoside), with CAS number 18997-57-4, has a molecular formula of C16H18O8 and a molecular weight of 338.309. It appears as a white to almost white powder or crystal, with a melting point of 258-263°C (decomposition). For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Methylumbelliferyl-β-D-glucopyranoside |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2]. |
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| Related Catalog | |
| Target |
4-Methylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 626.9±55.0 °C at 760 mmHg |
| Melting Point | 258-263ºC (dec.) |
| Molecular Formula | C16H18O8 |
| Molecular Weight | 338.309 |
| Flash Point | 233.9±25.0 °C |
| Exact Mass | 338.100159 |
| PSA | 129.59000 |
| LogP | -0.46 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.641 |
| InChIKey | YUDPTGPSBJVHCN-YMILTQATSA-N |
| SMILES | Cc1cc(=O)oc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12 |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | T+ |
| Risk Phrases | 26/27/28 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932999099 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
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| DownStream 7 | |
CAS#:67909-25-5
CAS#:90-33-5
CAS#:572-09-8
CAS#:604-68-2
CAS#:83-87-4
CAS#:3947-62-4
CAS#:74808-10-9
CAS#:618879-31-5
CAS#:618879-32-6
CAS#:133-89-1
CAS#:2280-44-6
CAS#:492-61-5
CAS#:50-99-7
CAS#:72626-61-0
CAS#:172364-08-8
CAS#:6160-80-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Chemical conversion of self-assembled hexadecyl monolayers with active oxygen species generated by vacuum ultraviolet irradiation in an atmospheric environment.
Soft Matter 11 , 5678-87, (2015) Vacuum ultraviolet (VUV, λ = 172 nm) irradiation of alkyl self-assembled monolayers (SAMs) in the presence of dry air alters their surface properties. In this work, UV photochemically prepared hexadec... |
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Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency.
J. Clin. Immunol. 35 , 373-83, (2015) Hematopoietic cell transplantation (HCT) provides a curative therapy for severe forms of primary immunodeficiencies (PID). While the timing and extent of T-cell reconstitution following transplant for... |
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Impact of very early CD4(+) /CD8(+) T cell counts on the occurrence of acute graft-versus-host disease and NK cell counts on outcome after pediatric allogeneic hematopoietic stem cell transplantation.
Pediatr. Blood Cancer 62(3) , 522-8, (2015) Increasing evidence suggests that early and rapid lymphocyte recovery following allogeneic hematopoietic stem cell transplantation (HSCT) is associated with better survival.We retrospectively analyzed... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: pKa (acid-base dissociation constant) as determined by Avdeef ref: DOI: 10.1002/04714...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2449007
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Name: Metabolic stability in rat liver homogenate assessed as compound hydrolysis at 10 uM ...
Source: ChEMBL
Target: Liver
External Id: CHEMBL3802103
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Inhibition of human full-length cytosolic CA1 after 6 hrs by stopped flow CO2 hydrati...
Source: ChEMBL
Target: Carbonic anhydrase 1
External Id: CHEMBL1941821
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 7-hydroxy-4-methyl-8-nitro-chromen-2-one |
| 4-methylumbelliferyl β-D-glucoside |
| 4-Methyl-2-oxo-2H-chromen-7-yl β-D-glucopyranoside |
| 4-methyl-7-hydroxy-8-nitro coumarin |
| EINECS 228-185-5 |
| 4-methyl-8-nitro-7-hydroxycoumarin |
| 4-Methylumbelliferyl-beta-D-glucopyranoside |
| MFCD00036773 |
| mutanolysin |
| 7-Hydroxy-4-methyl-8-nitro-cumarin |
| (4-Methylumbelliferone)-β-D-glucopyranoside |
| 7-hydroxy-4-methyl-8-nitro-coumarin |
| 7-hydroxy-8-nitro-4-methyl-2H-chromen-2-one |
| 4-Methylumbelliferyl β-D-glucopyranoside |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: CAS number of 4-Methylumbelliferyl-β-D-glucopyranoside is 18997-57-4. |
| Q: What are the uses of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: Main uses of 4-Methylumbelliferyl-β-D-glucopyranoside: 4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2]. |
| Q: What is the InChIKey of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: InChIKey of 4-Methylumbelliferyl-β-D-glucopyranoside is YUDPTGPSBJVHCN-YMILTQATSA-N. |
| Q: What is the molecular formula of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: Molecular formula of 4-Methylumbelliferyl-β-D-glucopyranoside is C16H18O8. |
| Q: What are the storage conditions for 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: Storage conditions for 4-Methylumbelliferyl-β-D-glucopyranoside: 2-8°C. |
| Q: What is the boiling point of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: Boiling point of 4-Methylumbelliferyl-β-D-glucopyranoside is 626.9±55.0 °C at 760 mmHg. |
| Q: What are the upstream materials of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: Related upstream materials(CAS) of 4-Methylumbelliferyl-β-D-glucopyranoside: 67909-25-5;90-33-5;572-09-8;604-68-2;83-87-4;3947-62-4;74808-10-9;618879-31-5;618879-32-6;133-89-1. |
| Q: What is the SMILES notation of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: SMILES notation of 4-Methylumbelliferyl-β-D-glucopyranoside is Cc1cc(=O)oc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12. |
| Q: What is the English name of 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: The English name of 4-Methylumbelliferyl-β-D-glucopyranoside is 4-Methylumbelliferyl-β-D-glucopyranoside. |
| Q: What is the safety information for 4-Methylumbelliferyl-β-D-glucopyranoside? |
| A: Safety information for 4-Methylumbelliferyl-β-D-glucopyranoside: 22-24/25. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |