LY 338979

Modify Date: 2025-08-24 23:25:28

LY 338979 Structure
LY 338979 structure
Common Name LY 338979
CAS Number 193281-00-4 Molecular Weight 443.41
Density N/A Boiling Point N/A
Molecular Formula C20H21N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY 338979


LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820)[1].

 Names

Name (2R)-2-[[4-[2-(2-amino-4,6-dioxo-5,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
Synonym More Synonyms

 LY 338979 Biological Activity

Description LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820)[1].
Related Catalog
References

[1]. Woodland JM, et al. Metabolism and disposition of the antifolate LY231514 in mice and dogs. Drug Metab Dispos. 1997 Jun;25(6):693-700.  

 Chemical & Physical Properties

Molecular Formula C20H21N5O7
Molecular Weight 443.41
Exact Mass 443.14400
PSA 209.05000
LogP 0.88680

 Synonyms

N-[4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid
2-{4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethyl]-benzoylamino}-pentanedioic acid
LY 338979
Pemetrexed Impurity 18
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