AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2

Modify Date: 2025-08-23 00:36:56

AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2 structure	Common Name	AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2
	CAS Number	200959-47-3	Molecular Weight	1012.17000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₉H₆₉N₁₅O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2

Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors[1].

Name	Ac-RYYRWK-NH2
Synonym	More Synonyms

Description	Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	Kd: 0.071 nM (ORL1 in rat cortical membranes)[1]
References	[1]. C T Dooley, et al. Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1.J Pharmacol Exp Ther. 1997 Nov;283(2):735-41. [2]. M Ho, et al, Characterization of the ORL(1) receptor on adrenergic nerves in the rat anococcygeus muscle. Br J Pharmacol. 2000 Sep;131(2):349-55.

Molecular Formula	C₄₉H₆₉N₁₅O₉
Molecular Weight	1012.17000
Exact Mass	1011.54000
PSA	423.76000
LogP	4.80440
InChIKey	YROQVQIJRORFAZ-SKGSPYGFSA-N
SMILES	CC(=O)NC(CCCN=C(N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(N)=O

Name: Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrica...
Source: ChEMBL
Target: Nociceptin receptor
External Id: CHEMBL2404600

Name: Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrica...
Source: ChEMBL
Target: Nociceptin receptor
External Id: CHEMBL2405349

Name: Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrica...
Source: ChEMBL
Target: Nociceptin receptor
External Id: CHEMBL2405347

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AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2

Ac-RYYRWK amide

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China
Product Name: Ac-RYYRWK-NH2
Price: Check
Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: AC-RYYRWK-NH2
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Use of AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2

Names

AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2 Biological Activity

Chemical & Physical Properties

AC-ARG-TYR-TYR-ARG-TRP-LYS-NH2Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.