Procyanidin B1
Procyanidin B1 structure
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Common Name | Procyanidin B1 | ||
|---|---|---|---|---|
| CAS Number | 20315-25-7 | Molecular Weight | 578.520 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 955.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C30H26O12 | Melting Point | 231～232℃ | |
| MSDS | USA | Flash Point | 531.6±34.3 °C | |
Use of Procyanidin B1Procyanidin B1 is a polyphenolic flavonoid isolated from commonly eaten fruits, binds to TLR4/MD-2 complex, and has anti-inflammatory activity. |
| Name | procyanidin b1 |
|---|---|
| Synonym | More Synonyms |
| Description | Procyanidin B1 is a polyphenolic flavonoid isolated from commonly eaten fruits, binds to TLR4/MD-2 complex, and has anti-inflammatory activity. |
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| Related Catalog | |
| In Vitro | Procyanidin B1 is a polyphenolic flavonoid isolated from fruits and fruit juices, binds to TLR4/MD-2 complex, and has anti-inflammatory activity. Procyanidin B1 causes cellular toxicity at concentrations >100 μg/mL. Procyanidin B1 (100 μg/mL) inhibits LPS-induced TNF-α production, and expression of MD-2, TRAF6, NF-κB mRNA, phosphorylated p38 MAPK and NF-κB protein in THP1 cells[1]. Procyanidin B1 (50-100 µM) protects against Aβ oligomer-induced neuronal death. Procyanidin B1 potently inhibits the activation of caspase-3 at 100 µM, caspase-8 at concentrations of 30, 50, and 100 µM and caspase-9 at concentrations of 10, 30, 50, and 100 µM[2]. Procyanidin B1 (10, 20, 30 μM) significantly and dose-dependently induces expression of ACO and CPT1, with no obvious effect on mRNA expression of PPARα[3]. |
| Cell Assay | To investigate the cytotoxic effect of Procyanidin B1, viability of THP1 cells is assessed using CCK8 assay. THP1 cells are treated with Procyanidin B1 for 18 h, and 10 μL of CCK8 solution is then added to each well and the cultures are incubated for 4 h at 37°C. The optical density (OD) at 450 nm is measured using an ELx808 Absorbance Microplate Reader. The Procyanidin B1 concentration tested ranges from 50 to 200 μg/mL. Each sample is tested in triplicate[1]. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 955.3±65.0 °C at 760 mmHg |
| Melting Point | 231～232℃ |
| Molecular Formula | C30H26O12 |
| Molecular Weight | 578.520 |
| Flash Point | 531.6±34.3 °C |
| Exact Mass | 578.142456 |
| PSA | 220.76000 |
| LogP | 0.30 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.803 |
| Storage condition | 2-8°C |
| Precursor 6 | |
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| DownStream 4 | |
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CAS#:490-46-0![[4,8]-2,3-cis-3,4-trans:2,3-trans-octa-O-benzyl-(-)-3-O-acetyl-(-)-epicatechin-(+)-catechin Structure](https://image.chemsrc.com/caspic/357/664351-42-2.png)
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Effects of UV exclusion on the physiology and phenolic composition of leaves and berries of Vitis vinifera cv. Graciano.
J. Sci. Food Agric. 95(2) , 409-16, (2014) Ultraviolet (UV) radiation induces adaptive responses that can be used for plant production improvement. The aim of this study was to assess the effect of solar UV exclusion on the physiology and phen... |
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UHPLC-PDA-ESI/HRMSn profiling method to identify and quantify oligomeric proanthocyanidins in plant products.
J. Agric. Food Chem. 62(39) , 9387-400, (2014) Oligomeric proanthocyanidins were successfully identified by UHPLC-PDA-HRMS(n) in a selection of plant-derived materials (jujube fruit, Fuji apple, fruit pericarps of litchi and mangosteen, dark choco... |
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Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
Bioorg. Med. Chem. 18 , 28-35, (2010) The applicability of the newly developed RM1 and PM6 methods implemented in the semiempirical quantum chemistry mopac2009 software package in modeling free radical scavenging activity of flavonoids wa... |
| Proanthocyanidin B2 |
| (2R,2'R,3R,3'R,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-2H,2'H-4,8'-bichromene-3,3',5,5',7,7'-hexol |
| Proanthocyanidin B1 |
| 4,8"-Bi-[(+)-epicatechin] |
| PROCYANIDINDIMERB2 |
| ProcyanidinB1 |
| [4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-, (2R,2'R,3R,3'S,4R)- |
| Procyanidin B1 |
| Procyanidol B2 |
| Procyanidin B2 |
| Proanthocyanidin |
| UNII-L88HKE854X |
| (2R,2'R,3R,3'S,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-2H,2'H-4,8'-bichromene-3,3',5,5',7,7'-hexol |
| [4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-, (2R,2'R,3R,3'R,4R)- |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Procyanidin B1
- Price: Click To Check
- Purity: 95.0%
- Delivery: 10 Day
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- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Procyanidin B1
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Procyanidin B1
- Price: ￥1318.0/5mg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Procyanidin B1
- Price: $380.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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