AMPA Receptor Modulator-1

Modify Date: 2024-01-09 14:00:11

AMPA Receptor Modulator-1 Structure
AMPA Receptor Modulator-1 structure
Common Name AMPA Receptor Modulator-1
CAS Number 2036074-41-4 Molecular Weight 341.71
Density N/A Boiling Point N/A
Molecular Formula C16H11ClF3NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AMPA Receptor Modulator-1


AMPA Receptor Modulator is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].

 Names

Name AMPA Receptor Modulator

 AMPA Receptor Modulator-1 Biological Activity

Description AMPA Receptor Modulator is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].
Related Catalog
Target

pIC50: 9.7 (TARP γ-8)[1]

References

[1]. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.

 Chemical & Physical Properties

Molecular Formula C16H11ClF3NO2
Molecular Weight 341.71
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