AMPA Receptor Modulator-1

Modify Date: 2025-08-25 08:14:23

AMPA Receptor Modulator-1 Structure
AMPA Receptor Modulator-1 structure
Common Name AMPA Receptor Modulator-1
CAS Number 2036074-41-4 Molecular Weight 341.71
Density N/A Boiling Point N/A
Molecular Formula C16H11ClF3NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AMPA Receptor Modulator-1


AMPA Receptor Modulator is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].

 Names

Name AMPA Receptor Modulator

 AMPA Receptor Modulator-1 Biological Activity

Description AMPA Receptor Modulator is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].
Related Catalog
Target

pIC50: 9.7 (TARP γ-8)[1]

References

[1]. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.

 Chemical & Physical Properties

Molecular Formula C16H11ClF3NO2
Molecular Weight 341.71
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.