Thioquinapiperifil dihydrochloride
Modify Date: 2025-08-26 19:18:42
Thioquinapiperifil dihydrochloride structure
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Common Name | Thioquinapiperifil dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 204077-66-7 | Molecular Weight | 521.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H30Cl2N6OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thioquinapiperifil dihydrochlorideThioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2]. |
| Name | Thioquinapiperifil dihydrochloride |
|---|
| Description | Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2]. |
|---|---|
| Related Catalog | |
| Target |
PDE5:0.074 nM (IC50) PDE1:380 nM (IC50) PDE2:670 nM (IC50) PDE3:38 nM (IC50) PDE4:800 nM (IC50) |
| In Vitro | Thioquinapiperifil can be found in dietary supplements[1]. Thioquinapiperifil dihydrochloride (KF31327) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil dihydrochloride (KF31327) are required to inhibit platelet aggregation[2]. Thioquinapiperifil dihydrochloride (KF31327) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil dihydrochloride (KF31327)-treated cells is 0.95±0.17 pmol/108 cells[2]. |
| References |
| Molecular Formula | C24H30Cl2N6OS |
|---|---|
| Molecular Weight | 521.51 |
| InChIKey | YWGNFHIWAHNADT-UHFFFAOYSA-N |
| SMILES | CCn1c(=S)[nH]c2cc3c(NCc4ccccc4N4CCC(CO)CC4)ncnc3cc21.Cl.Cl |