NH-bis(m-PEG8)

Modify Date: 2024-01-09 17:03:54

NH-bis(m-PEG8) Structure
NH-bis(m-PEG8) structure
Common Name NH-bis(m-PEG8)
CAS Number 2055013-64-2 Molecular Weight 749.92
Density N/A Boiling Point N/A
Molecular Formula C34H71NO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH-bis(m-PEG8)


NH-bis(m-PEG8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH-bis(m-PEG8)
Synonym More Synonyms

 NH-bis(m-PEG8) Biological Activity

Description NH-bis(m-PEG8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H71NO16
Molecular Weight 749.92

 Synonyms

MFCD28015763
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