Propargyl-PEG8-Boc

Modify Date: 2024-01-08 18:08:10

Propargyl-PEG8-Boc Structure
Propargyl-PEG8-Boc structure
Common Name Propargyl-PEG8-Boc
CAS Number 2055014-96-3 Molecular Weight 492.600
Density 1.1±0.1 g/cm3 Boiling Point 528.4±45.0 °C at 760 mmHg
Molecular Formula C24H44O10 Melting Point N/A
MSDS N/A Flash Point 220.3±28.8 °C

 Use of Propargyl-PEG8-Boc


Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG8-t-butyl ester
Synonym More Synonyms

 Propargyl-PEG8-Boc Biological Activity

Description Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 528.4±45.0 °C at 760 mmHg
Molecular Formula C24H44O10
Molecular Weight 492.600
Flash Point 220.3±28.8 °C
Exact Mass 492.293457
LogP -0.54
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.460
Storage condition 2-8°C

 Synonyms

2-Methyl-2-propanyl 4,7,10,13,16,19,22,25-octaoxaoctacos-27-yn-1-oate
MFCD28976700
4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid, 1,1-dimethylethyl ester
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