Propargyl-PEG8-acid

Modify Date: 2024-01-10 14:20:17

Propargyl-PEG8-acid Structure
Propargyl-PEG8-acid structure
Common Name Propargyl-PEG8-acid
CAS Number 2055014-94-1 Molecular Weight 436.494
Density 1.1±0.1 g/cm3 Boiling Point 531.0±50.0 °C at 760 mmHg
Molecular Formula C20H36O10 Melting Point N/A
MSDS N/A Flash Point 171.9±23.6 °C

 Use of Propargyl-PEG8-acid


Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1].

 Names

Name Propargyl-PEG8-acid
Synonym More Synonyms

 Propargyl-PEG8-acid Biological Activity

Description Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 531.0±50.0 °C at 760 mmHg
Molecular Formula C20H36O10
Molecular Weight 436.494
Flash Point 171.9±23.6 °C
Exact Mass 436.230835
LogP -2.23
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.469

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD28976699
4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid
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