N-(Mal-PEG6)-N-bis(PEG3-amine) TFA

Modify Date: 2023-01-16 10:31:50

N-(Mal-PEG6)-N-bis(PEG3-amine) TFA Structure
N-(Mal-PEG6)-N-bis(PEG3-amine) TFA structure
Common Name N-(Mal-PEG6)-N-bis(PEG3-amine) TFA
CAS Number 2055040-99-6 Molecular Weight 853.99
Density N/A Boiling Point N/A
Molecular Formula C38H71N5O16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Mal-PEG6)-N-bis(PEG3-amine) TFA


N-(Mal-PEG6)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Mal-PEG6)-N-bis(PEG3-amine)

 N-(Mal-PEG6)-N-bis(PEG3-amine) TFA Biological Activity

Description N-(Mal-PEG6)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C38H71N5O16
Molecular Weight 853.99
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