N-Mal-N-bis(PEG4-NH-Boc)

Modify Date: 2024-01-10 10:04:33

N-Mal-N-bis(PEG4-NH-Boc) Structure
N-Mal-N-bis(PEG4-NH-Boc) structure
Common Name N-Mal-N-bis(PEG4-NH-Boc)
CAS Number 2128735-27-1 Molecular Weight 806.94
Density N/A Boiling Point N/A
Molecular Formula C37H66N4O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Mal-N-bis(PEG4-NH-Boc)


N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Mal-N-bis(PEG4-NH-Boc)
Synonym More Synonyms

 N-Mal-N-bis(PEG4-NH-Boc) Biological Activity

Description N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C37H66N4O15
Molecular Weight 806.94

 Synonyms

MFCD31536761
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