N-Mal-N-bis(PEG4-acid)

Modify Date: 2024-01-06 09:23:19

N-Mal-N-bis(PEG4-acid) Structure
N-Mal-N-bis(PEG4-acid) structure
Common Name N-Mal-N-bis(PEG4-acid)
CAS Number 2100306-52-1 Molecular Weight 664.70
Density N/A Boiling Point N/A
Molecular Formula C29H48N2O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Mal-N-bis(PEG4-acid)


Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-N-bis(PEG4-C2-acid)
Synonym More Synonyms

 N-Mal-N-bis(PEG4-acid) Biological Activity

Description Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H48N2O15
Molecular Weight 664.70

 Synonyms

MFCD29912655