Azido-PEG3-S-PEG4-t-butyl ester

Modify Date: 2025-09-10 20:40:08

Azido-PEG3-S-PEG4-t-butyl ester Structure
Azido-PEG3-S-PEG4-t-butyl ester structure
 Common Name Azido-PEG3-S-PEG4-t-butyl ester
CAS Number 2055041-19-3 Molecular Weight 539.68
Density N/A Boiling Point N/A
Molecular Formula C23H45N3O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-S-PEG4-t-butyl ester


Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-S-PEG4-t-butyl ester

 Azido-PEG3-S-PEG4-t-butyl ester Biological Activity

Description Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H45N3O9S
Molecular Weight 539.68
InChIKey UPJKMGHIPNYNEY-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)CCOCCOCCOCCOCCSCCOCCOCCOCCN=[N+]=[N-]
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