Azido-PEG4-Boc

Modify Date: 2024-01-14 17:57:07

Azido-PEG4-Boc Structure
Azido-PEG4-Boc structure
Common Name Azido-PEG4-Boc
CAS Number 581066-04-8 Molecular Weight 347.407
Density N/A Boiling Point N/A
Molecular Formula C15H29N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG4-Boc


Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
Synonym More Synonyms

 Azido-PEG4-Boc Biological Activity

Description Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H29N3O6
Molecular Weight 347.407
Exact Mass 347.205627
LogP 0.63
Storage condition 2-8°C

 Synonyms

2-Methyl-2-propanyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate
3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-azido-, 1,1-dimethylethyl ester
Azido-PEG5-t-butyl ester
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