IWP-O1

Modify Date: 2024-01-05 18:09:06

IWP-O1 structure	Common Name	IWP-O1
	CAS Number	2074607-48-8	Molecular Weight	432.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₀N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IWP-O1

IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells, suppressing the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. IWP-O1 functions by preventing the secretion of Wnt proteins[1].

Name	IWP-O1

Description	IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells, suppressing the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. IWP-O1 functions by preventing the secretion of Wnt proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt Signaling Pathways >> Stem Cell/Wnt >> Porcupine
Target	EC50: 80 pM (Porcn)[1].
References	[1]. You L, et al. Development of a triazole class of highly potent Porcn inhibitors. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5891-5895.

Molecular Formula	C₂₆H₂₀N₆O
Molecular Weight	432.48
Storage condition	-20℃

DC Chemicals Limited
China
Product Name: IWP-O1
Price: $550.0/100mg $1100.0/250mg $2200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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