IWP-O1
Modify Date: 2025-08-21 16:35:58
IWP-O1 structure
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Common Name | IWP-O1 | ||
|---|---|---|---|---|
| CAS Number | 2074607-48-8 | Molecular Weight | 432.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H20N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IWP-O1IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells, suppressing the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. IWP-O1 functions by preventing the secretion of Wnt proteins[1]. |
| Name | IWP-O1 |
|---|
| Description | IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells, suppressing the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. IWP-O1 functions by preventing the secretion of Wnt proteins[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 80 pM (Porcn)[1]. |
| References |
| Molecular Formula | C26H20N6O |
|---|---|
| Molecular Weight | 432.48 |
| Storage condition | -20℃ |