N-(Amino-PEG5)-N-bis(PEG4-acid)

Modify Date: 2024-01-31 07:33:04

N-(Amino-PEG5)-N-bis(PEG4-acid) Structure
N-(Amino-PEG5)-N-bis(PEG4-acid) structure
Common Name N-(Amino-PEG5)-N-bis(PEG4-acid)
CAS Number 2093152-86-2 Molecular Weight 776.91
Density N/A Boiling Point N/A
Molecular Formula C34H68N2O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Amino-PEG5)-N-bis(PEG4-acid)


N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker used in the synthesis of PROTACs. N-(Amino-PEG5)-N-bis(PEG4-acid) contains an amino group with two terminal carboxylic acids[1].

 Names

Name N-(Amino-PEG5)-N-bis(PEG4-acid)

 N-(Amino-PEG5)-N-bis(PEG4-acid) Biological Activity

Description N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker used in the synthesis of PROTACs. N-(Amino-PEG5)-N-bis(PEG4-acid) contains an amino group with two terminal carboxylic acids[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Pignatello, R., et al. New amphiphilic derivatives of poly(ethylene glycol) (PEG) as surface modifiers of colloidal drug carriers. III. Lipoamino acid conjugates with carboxy- and amino-PEG5000 polymers. Materials Science and Engineering: C, 2015.46, 470–481.

 Chemical & Physical Properties

Molecular Formula C34H68N2O17
Molecular Weight 776.91
Storage condition 2-8°C
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