N-Biotin-N-bis(PEG4-acid)

Modify Date: 2024-01-10 10:47:18

N-Biotin-N-bis(PEG4-acid) Structure
N-Biotin-N-bis(PEG4-acid) structure
Common Name N-Biotin-N-bis(PEG4-acid)
CAS Number 1964503-35-2 Molecular Weight 739.87
Density N/A Boiling Point N/A
Molecular Formula C32H57N3O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Biotin-N-bis(PEG4-acid)


N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Biotin-N-bis(PEG4-acid)
Synonym More Synonyms

 N-Biotin-N-bis(PEG4-acid) Biological Activity

Description N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C32H57N3O14S
Molecular Weight 739.87

 Synonyms

MFCD30458057