TP-030-1

Modify Date: 2025-08-26 19:11:26

TP-030-1 Structure
TP-030-1 structure
 Common Name TP-030-1
CAS Number 2095514-75-1 Molecular Weight 402.45
Density N/A Boiling Point N/A
Molecular Formula C23H22N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TP-030-1


TP-030-1 is an inhibitor of RIPK1. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM and inhibits mRIPK1 with an IC50 value of 4.2 μM. TP-030-1 can be used for the research of inflammatory diseases and neurodegenerative diseases[1].

 Names

Name TP-030-1

 TP-030-1 Biological Activity

Description TP-030-1 is an inhibitor of RIPK1. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM and inhibits mRIPK1 with an IC50 value of 4.2 μM. TP-030-1 can be used for the research of inflammatory diseases and neurodegenerative diseases[1].
Related Catalog
In Vitro TP-030-1 inhibits HT29 necroptosis with an IC50 value of 18 nM[1]. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM[1]. TP-030-1 inhibits mRIPK1 with an IC50 value of 4.2 μM[1].
References

[1]. Msato Yoshikawa, et al. Discovery of 7-Oxo-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure–Kinetic Relationships. J. Med. Chem. 2018, 61, 6, 2384–2409.

 Chemical & Physical Properties

Molecular Formula C23H22N4O3
Molecular Weight 402.45
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Chemsrc provides TP-030-1(CAS#:2095514-75-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TP-030-1 are included as well.>> amp version: TP-030-1

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