Propargyl-PEG5-CH2CO2tBu

Modify Date: 2024-01-10 19:44:11

Propargyl-PEG5-CH2CO2tBu Structure
Propargyl-PEG5-CH2CO2tBu structure
Common Name Propargyl-PEG5-CH2CO2tBu
CAS Number 2098489-63-3 Molecular Weight 346.42
Density N/A Boiling Point N/A
Molecular Formula C17H30O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG5-CH2CO2tBu


Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG4-O-C1-Boc

 Propargyl-PEG5-CH2CO2tBu Biological Activity

Description Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461.

 Chemical & Physical Properties

Molecular Formula C17H30O7
Molecular Weight 346.42
Storage condition 2-8°C