N-(Acid-PEG2)-N-bis(PEG2-propargyl)

Modify Date: 2024-01-10 20:33:52

N-(Acid-PEG2)-N-bis(PEG2-propargyl) Structure
N-(Acid-PEG2)-N-bis(PEG2-propargyl) structure
Common Name N-(Acid-PEG2)-N-bis(PEG2-propargyl)
CAS Number 2100306-49-6 Molecular Weight 429.50
Density N/A Boiling Point N/A
Molecular Formula C21H35NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Acid-PEG2)-N-bis(PEG2-propargyl)


N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(PEG2-C2-acid)-N-bis(PEG2-propargyl)
Synonym More Synonyms

 N-(Acid-PEG2)-N-bis(PEG2-propargyl) Biological Activity

Description N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H35NO8
Molecular Weight 429.50

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30723247