N-(PEG1-OH)-N-Boc-PEG2-propargyl

Modify Date: 2025-09-13 12:43:59

N-(PEG1-OH)-N-Boc-PEG2-propargyl Structure
N-(PEG1-OH)-N-Boc-PEG2-propargyl structure
Common Name N-(PEG1-OH)-N-Boc-PEG2-propargyl
CAS Number 2100306-85-0 Molecular Weight 331.40
Density N/A Boiling Point N/A
Molecular Formula C16H29NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(PEG1-OH)-N-Boc-PEG2-propargyl


N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(PEG1-OH)-N-Boc-PEG2-propargyl
Synonym More Synonyms

 N-(PEG1-OH)-N-Boc-PEG2-propargyl Biological Activity

Description N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H29NO6
Molecular Weight 331.40
InChIKey YEBWOLWOJRIJNN-UHFFFAOYSA-N
SMILES C#CCOCCOCCN(CCOCCO)C(=O)OC(C)(C)C

 Synonyms

MFCD30730381
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