t-Boc-Aminooxy-PEG1-azide

Modify Date: 2024-01-11 19:26:28

t-Boc-Aminooxy-PEG1-azide Structure
t-Boc-Aminooxy-PEG1-azide structure
Common Name t-Boc-Aminooxy-PEG1-azide
CAS Number 2100306-67-8 Molecular Weight 246.26
Density N/A Boiling Point N/A
Molecular Formula C9H18N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG1-azide


Boc-Aminooxy-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG1-azide

 t-Boc-Aminooxy-PEG1-azide Biological Activity

Description Boc-Aminooxy-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C9H18N4O4
Molecular Weight 246.26
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