CHK1-IN-4

Modify Date: 2024-01-09 19:05:50

CHK1-IN-4 structure	Common Name	CHK1-IN-4
	CAS Number	2120398-41-4	Molecular Weight	444.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₈BrN₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CHK1-IN-4

CHK1-IN-4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity[1].

Name	CHK1-IN-4

Description	CHK1-IN-4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity[1].
Related Catalog	Research Areas >> Cancer
Target	Chk1
In Vivo	CHK1-IN-4 (Compound 3) (40 mg/kg, IV, twice a week) alone enhances anti-tumor growth activity of CPT1 in the tumor model[1].
References	[1]. Xiong Cai, et al. 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (chk1) inhibitors, and their preparations and applications. WO2017132928A1.

Molecular Formula	C₁₈H₁₈BrN₇O₂
Molecular Weight	444.29

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CHK1-IN-4
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Purity: 98.0%
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