Org 37684

Modify Date: 2024-01-10 18:44:12

Org 37684 Structure
Org 37684 structure
Common Name Org 37684
CAS Number 213007-95-5 Molecular Weight 269.767
Density N/A Boiling Point N/A
Molecular Formula C14H20ClNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Org 37684


Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor[1].

 Names

Name (S)-3-((5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy)pyrrolidine hydrochloride
Synonym More Synonyms

 Org 37684 Biological Activity

Description Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor[1].
Related Catalog
In Vitro Org37684 is an agonist at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells[1].
References

[1]. Porter RH, et al. Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. Br J Pharmacol. 1999;128(1):13-20.

 Chemical & Physical Properties

Molecular Formula C14H20ClNO2
Molecular Weight 269.767
Exact Mass 269.118256

 Synonyms

Pyrrolidine, 3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy]-, (3S)-, hydrochloride (1:1)
(S)-3-((5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy)pyrrolidine hydrochloride
(3S)-3-[(5-Methoxy-2,3-dihydro-1H-inden-4-yl)oxy]pyrrolidine hydrochloride (1:1)
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