Flumethasone
Modify Date: 2025-08-20 19:29:19
Flumethasone structure
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Common Name | Flumethasone | ||
|---|---|---|---|---|
| CAS Number | 2135-17-3 | Molecular Weight | 410.452 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 569.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H28F2O5 | Melting Point | 237-240ºC | |
| MSDS | Chinese USA | Flash Point | 298.4±30.1 °C | |
| Symbol |
GHS08 |
Signal Word | Warning | |
Use of FlumethasoneFlumethasone is a corticosteroid for topical use, in combination with Clioquinol for the treatment of otitis externa and otomycosis. Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity. |
| Name | flumethasone |
|---|---|
| Synonym | More Synonyms |
| Description | Flumethasone is a corticosteroid for topical use, in combination with Clioquinol for the treatment of otitis externa and otomycosis. Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 569.8±50.0 °C at 760 mmHg |
| Melting Point | 237-240ºC |
| Molecular Formula | C22H28F2O5 |
| Molecular Weight | 410.452 |
| Flash Point | 298.4±30.1 °C |
| Exact Mass | 410.190491 |
| PSA | 94.83000 |
| LogP | 1.61 |
| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
| Index of Refraction | 1.579 |
| InChIKey | WXURHACBFYSXBI-GQKYHHCASA-N |
| SMILES | CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R40 |
| Safety Phrases | S22-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | TU3832000 |
| HS Code | 2937229000 |
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Flumethasone CAS#:2135-17-3 |
| Literature: WO2012/11106 A1, ; Page/Page column 20 ; |
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Flumethasone CAS#:2135-17-3 |
| Literature: Farmaco, , vol. 51, # 12 p. 809 - 810 |
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Flumethasone CAS#:2135-17-3 |
| Literature: WO2012/11106 A1, ; |
CAS#:2607-06-9
CAS#:28416-82-2| HS Code | 2937229000 |
|---|
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Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.
Food. Addit. Contam. Part. B. Surveill. 8 , 106-12, (2015) The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test pro... |
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Lecithin based nanoemulsions: A comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation.
Int. J. Pharm. 370(1-2) , 181-6, (2009) Charged drug delivery systems are interesting candidates for the delivery of drugs through skin. In the present study, it was possible to create negatively and positively charged oil/water nanoemulsio... |
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Tympanoplasty graft preparation using ear drops containing polyethylene glycol, flumethasone and clioquinol.
J. Laryngol. Otol. 125(8) , 853-5, (2011) The aim of tympanoplasty graft preparation is to stiffen the fascia or perichondrium and thereby to optimise ease of manipulation. We report 39 cases utilising a novel technique in which the graft is ... |
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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|
Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ant...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p
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| 6a-Fluorodexamethasone |
| (6α,11β,16α)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| 6α-Fluorodexamethasone |
| 6α,9α-Difluoro-16α-methylprednisolone |
| Aniprime |
| Flumethasone |
| (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluor-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-on |
| Fluvet |
| EINECS 218-370-9 |
| flumetasone |
| 6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione |
| Flucorticin |
| Anaprime |
| (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one |
| MFCD00056464 |
| Flumethason |
| Cortexilar |
| 6a,9a-Difluoro-16a-methylprednisolone |
| Methagon |
| (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |