THAL SNS 032
THAL SNS 032 structure
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Common Name | THAL SNS 032 | ||
|---|---|---|---|---|
| CAS Number | 2139287-33-3 | Molecular Weight | 869.02 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H52N8O10S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of THAL SNS 032THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN)[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | THAL-SNS-032 |
|---|
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN)[1]. |
|---|---|
| Related Catalog | |
| Target |
CDK9[1] |
| In Vitro | THAL-SNS-032 selectively induces degradation of CDK9[1]. THAL-SNS-032 diminishes elongating polymerase II[1]. THAL-SNS-032 inhibits proliferation of MOLT4 cells with an IC50 of 50 nM[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C40H52N8O10S2 |
|---|---|
| Molecular Weight | 869.02 |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of THAL-SNS-032? |
| A: CAS number of THAL-SNS-032 is 2139287-33-3. |
| Q: What is the molecular weight of THAL-SNS-032? |
| A: Molecular weight of THAL-SNS-032 is 869.02. |
| Q: What is the English name of THAL-SNS-032? |
| A: The English name of THAL-SNS-032 is THAL-SNS-032. |
| Q: What is the molecular formula of THAL-SNS-032? |
| A: Molecular formula of THAL-SNS-032 is C40H52N8O10S2. |
| Q: What are the uses of THAL-SNS-032? |
| A: Main uses of THAL-SNS-032: THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN)[1]. |
| Q: What is the Chinese name of 2139287-33-3? |
| A: Chinese name of 2139287-33-3 is THAL-SNS-032. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |