Boc-Cys(Trt)-OH

Modify Date: 2024-01-02 10:35:51

Boc-Cys(Trt)-OH Structure
Boc-Cys(Trt)-OH structure
Common Name Boc-Cys(Trt)-OH
CAS Number 21947-98-8 Molecular Weight 463.589
Density 1.2±0.1 g/cm3 Boiling Point 610.9±55.0 °C at 760 mmHg
Molecular Formula C27H29NO4S Melting Point 143-146 °C(lit.)
MSDS USA Flash Point 323.3±31.5 °C

 Use of Boc-Cys(Trt)-OH


(R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid is a cysteine derivative[1].

 Names

Name (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoic acid
Synonym More Synonyms

 Boc-Cys(Trt)-OH Biological Activity

Description (R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid is a cysteine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 610.9±55.0 °C at 760 mmHg
Melting Point 143-146 °C(lit.)
Molecular Formula C27H29NO4S
Molecular Weight 463.589
Flash Point 323.3±31.5 °C
Exact Mass 463.181732
PSA 100.93000
LogP 7.52
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.596

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~89%

Boc-Cys(Trt)-OH Structure

Boc-Cys(Trt)-OH

CAS#:21947-98-8

Literature: Venkateswara Rao, Boddu; Dhokale, Snehal; Rajamohanan, Pattuparambil R.; Hotha, Srinivas Chemical Communications, 2013 , vol. 49, # 92 p. 10808 - 10810

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Boc-Cys(Trt)-OH Structure

Boc-Cys(Trt)-OH

CAS#:21947-98-8

Literature: Organic Letters, , vol. 7, # 13 p. 2615 - 2618

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Boc-Cys(Trt)-OH Structure

Boc-Cys(Trt)-OH

CAS#:21947-98-8

Literature: European Journal of Medicinal Chemistry, , vol. 50, p. 383 - 392

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Boc-Cys(Trt)-OH Structure

Boc-Cys(Trt)-OH

CAS#:21947-98-8

Literature: Chemische Berichte, , vol. 102, p. 1048 - 1052

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Boc-Cys(Trt)-OH Structure

Boc-Cys(Trt)-OH

CAS#:21947-98-8

Literature: Canadian Journal of Chemistry, , vol. 57, p. 1388 - 1396

 Preparation


 Articles1

More Articles
Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Bioorg. Med. Chem. Lett. 17 , 3921-4, (2007)

Inhibition of Eg5 represents a novel approach for the treatment of cancer. Here, we report the synthesis and structure-activity relationship of S-trityl-L-cysteine (STLC) derivatives as Eg5 inhibitors...

 Synonyms

L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(triphenylmethyl)-
MFCD00038251
(R)-2-(tert-Butoxycarbonylamino)-3-(tritylthio)propanoic acid
N-[(1,1-dimethylethoxy)carbonyl]-S-trityl-L-cysteine
n-(tert-butoxycarbonyl)-s-trityl-l-cysteine
S-trityl-N-Boc-(R)-cysteine
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-S-trityl-L-cysteine
N-t-butyloxycarbonyl-S-trityl-L-cysteine
S-trityl-N-Boc-cysteine
N-t-butoxycarbonyl-S-trityl-L-Cysteine
Boc-S-trityl-L-cysteine
Boc-Cys(Trt)-OH
EINECS 244-674-6
N-Boc-S-trityl-L-cysteine
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