PF-06815189
Modify Date: 2024-06-06 18:43:36
PF-06815189 structure
|
Common Name | PF-06815189 | ||
|---|---|---|---|---|
| CAS Number | 2218484-75-2 | Molecular Weight | 418.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H17F3N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-06815189PF-06815189 is a potent, selective phosphodiesterase 2 (PDE2) inhibitor with IC50 of 0.4 nM, >1,000-fold selectivity over PDE5; also demonstrates no significant activities (EC50 >10 μM) in a broad spectrum BioPrint panel; possesses favorable pharmacological and in vitro ADME profile, the pharmacokinetic attributes. |
| Name | PF-06815189 |
|---|
| Description | PF-06815189 is a potent, selective phosphodiesterase 2 (PDE2) inhibitor with IC50 of 0.4 nM, >1,000-fold selectivity over PDE5; also demonstrates no significant activities (EC50 >10 μM) in a broad spectrum BioPrint panel; possesses favorable pharmacological and in vitro ADME profile, the pharmacokinetic attributes. |
|---|---|
| References | References 1. Stepan AF, et al. ACS Med Chem Lett. 2018 Jan 4;9(2):68-72. View Related Products by Target Phosphodiesterase (PDE) |
| Molecular Formula | C19H17F3N6O2 |
|---|---|
| Molecular Weight | 418.38 |