PF-04531083

Modify Date: 2025-08-26 10:10:29

PF-04531083 Structure
PF-04531083 structure
Common Name PF-04531083
CAS Number 1079400-07-9 Molecular Weight 357.794
Density 1.4±0.1 g/cm3 Boiling Point 471.0±45.0 °C at 760 mmHg
Molecular Formula C17H16ClN5O2 Melting Point N/A
MSDS USA Flash Point 238.7±28.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of PF-04531083


PF 04531083 is a selective NaV1.8 blocker, and used for the research of neuropathic/inflammatory pain.

 Names

Name PF 04531083
Synonym More Synonyms

 PF-04531083 Biological Activity

Description PF 04531083 is a selective NaV1.8 blocker, and used for the research of neuropathic/inflammatory pain.
Related Catalog
Target

NaV1.8[1]

References

[1]. Bagal SK, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 471.0±45.0 °C at 760 mmHg
Molecular Formula C17H16ClN5O2
Molecular Weight 357.794
Flash Point 238.7±28.7 °C
Exact Mass 357.099243
LogP 1.61
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.670

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
RIDADR NONH for all modes of transport

 Synonyms

40497CY7Y3
MFCD28411617
PF-04531083
N-[6-Amino-5-(2-chloro-5-methoxyphenyl)-2-pyridinyl]-1-methyl-1H-pyrazole-5-carboxamide
1H-Pyrazole-5-carboxamide, N-[6-amino-5-(2-chloro-5-methoxyphenyl)-2-pyridinyl]-1-methyl-
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