Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy-

Modify Date: 2025-08-26 19:41:05

Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy- structure	Common Name	Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy-
	CAS Number	22203-98-1	Molecular Weight	282.12
	Density	1.479g/cm3	Boiling Point	361.5ºC at 760 mmHg
	Molecular Formula	C₁₃H₉Cl₂NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	172.4ºC

Use of Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy-

SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].

Name	5-chloro-N-(3-chlorophenyl)-2-hydroxybenzamide
Synonym	More Synonyms

Description	SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
References	[1]. Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.

Density	1.479g/cm3
Boiling Point	361.5ºC at 760 mmHg
Molecular Formula	C₁₃H₉Cl₂NO₂
Molecular Weight	282.12
Flash Point	172.4ºC
Exact Mass	281.00100
PSA	49.33000
LogP	4.02430
Vapour Pressure	9.91E-06mmHg at 25°C
Index of Refraction	1.685
Storage condition	2-8°C

Hazard Codes	Xn
HS Code	2924299090

5-chlorosalicyl...

CAS#:321-14-2

3-Chloroaniline

CAS#:108-42-9

~87%

Benzamide,5-chl...

CAS#:22203-98-1

Literature: Imramovsky, Ales; Vinsova, Jarmila; Ferriz, Juana Monreal; Kunes, Jiri; Pour, Milan; Dolezal, Martin Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5007 - 5011

Precursor 2
CAS#:321-14-2 5-chlorosalicyl... CAS#:108-42-9 3-Chloroaniline
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3',5-dichlorosalicylanilide

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy-
Price: Check
Purity: 99.3%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.