Biotin-PEG4-Picolyl azide

Modify Date: 2025-08-26 17:41:27

Biotin-PEG4-Picolyl azide structure	Common Name	Biotin-PEG4-Picolyl azide
	CAS Number	2222687-71-8	Molecular Weight	622.74
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₄₂N₈O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Biotin-PEG4-Picolyl azide

Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG4-Picolyl azide

Description	Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₄₂N₈O₇S
Molecular Weight	622.74
InChIKey	MIIHOWLWUTYJDT-UHFFFAOYSA-N
SMILES	[N-]=[N+]=NCc1ccc(NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC2SCC3NC(=O)NC32)cn1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Biotin-PEG4-Picolyl azide
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Purity: 95.0%
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