PARP10-IN-3
Modify Date: 2024-04-05 22:00:08
PARP10-IN-3 structure
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Common Name | PARP10-IN-3 | ||
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| CAS Number | 2225800-19-9 | Molecular Weight | 256.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H12N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PARP10-IN-3PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively[1]. |
| Name | PARP10-IN-3 |
|---|
| Description | PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively[1]. |
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| Related Catalog | |
| Target |
human PARP10:480 nM (IC50) human PARP2:1.7 μM (IC50) human PARP15:1.7 μM (IC50) human TNKS2:6.5 μM (IC50) human PARP4:7 μM (IC50) human TNKS1:21 μM (IC50) human PARP14:41 μM (IC50) human PARP12:>10 μM (IC50) human PARP16:>10 μM (IC50) human PARP1:>100 μM (IC50) human PARP3:>100 μM (IC50) |
| In Vitro | PARP10-IN-3 (化合物 20) 在 HeLa-PARP10 细胞中通过克隆形成测定 (CFA) 的 IC50 为 1-2 μM[1]。 |
| References |
| Molecular Formula | C14H12N2O3 |
|---|---|
| Molecular Weight | 256.26 |
| Storage condition | -20°C |