KRAS inhibitor-15

Modify Date: 2024-01-16 12:29:41

KRAS inhibitor-15 structure	Common Name	KRAS inhibitor-15
	CAS Number	2230873-75-1	Molecular Weight	451.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₇Cl₂FN₄OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS inhibitor-15

KRAS inhibitor-15 (compound 3-19) is a potent KRAS G12C inhibitor with an IC50 of 0.954 µM. KRAS inhibitor-15 shows p-ERK inhibition activities with IC50s of 2.03, >33.3 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-15 has the potential for the research of pancreatic, colorectal, and lung cancers[1].

Name	KRAS inhibitor-15

Description	KRAS inhibitor-15 (compound 3-19) is a potent KRAS G12C inhibitor with an IC50 of 0.954 µM. KRAS inhibitor-15 shows p-ERK inhibition activities with IC50s of 2.03, >33.3 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-15 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:0.954 μM (IC50)
References	[1]. Brian alan, et al. KRAS g12c inhibitors and methods of using the same. WO2018119183 A2

Molecular Formula	C₂₀H₁₇Cl₂FN₄OS
Molecular Weight	451.34

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KRAS inhibitor-15

Use of KRAS inhibitor-15

Names

KRAS inhibitor-15 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.