Anticancer agent 56

Modify Date: 2025-08-26 20:22:35

Anticancer agent 56 Structure
Anticancer agent 56 structure
 Common Name Anticancer agent 56
CAS Number 2241915-59-1 Molecular Weight 383.83
Density N/A Boiling Point N/A
Molecular Formula C20H18ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anticancer agent 56


Anticancer agent 56 (compound 4d) is a potent anti-cancer agent with drug-likeness properties, possessing anticancer activity against several cancer cell lines (IC50<3 μM). Anticancer agent 56 induces cell cycle arrest at G2/M phase and triggers mitochondrial apoptosis pathway. Anticancer agent 56 acts by accumulation of ROS, up regulation of BAX, down regulation of Bcl-2 and activation of caspases 3, 7, 9[1].

 Names

Name Anticancer agent 56

 Anticancer agent 56 Biological Activity

Description Anticancer agent 56 (compound 4d) is a potent anti-cancer agent with drug-likeness properties, possessing anticancer activity against several cancer cell lines (IC50<3 μM). Anticancer agent 56 induces cell cycle arrest at G2/M phase and triggers mitochondrial apoptosis pathway. Anticancer agent 56 acts by accumulation of ROS, up regulation of BAX, down regulation of Bcl-2 and activation of caspases 3, 7, 9[1].
Related Catalog
Target

IC50: 0.64 ± 0.02 μM in Leukemia RPMI-8226, 0.96 ± 0.04 μM in Leukemia SR, 0.84 ± 0.07 μM in Leukemia K-562, 0.69 ± 0.01 μM in Melanoma M14, 0.24 ± 0.01 μM in Breast MCF7, 0.26 ± 0.01 μM in Colon HCT116, 2.95 ± 0.14 μM in Prostate PC3[1]

References

[1]. Ashour HF, et al. 1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226. Eur J Med Chem. 2020;189:112062.

 Chemical & Physical Properties

Molecular Formula C20H18ClN3O3
Molecular Weight 383.83
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