CC-92480

Modify Date: 2024-01-03 15:31:05

CC-92480 structure	Common Name	CC-92480
	CAS Number	2259648-80-9	Molecular Weight	567.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₃₀FN₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CC-92480

CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity[1].

Name	CC-92480
Synonym	More Synonyms

Description	CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity[1].
Related Catalog	Research Areas >> Cancer
In Vitro	CC-92480 is the second cereblon modulator. CC-92480-induced loss of Aiolos and Ikaros in cultures of PBMCs resulted in the activation of T cells and increased production of IL-2 and interferon γ. CC-92480 is effective in lenalidomide, pomalidomide, and CC-220-resistant cell lines. It exerts single-agent induction of apoptosis and exhibits remarkable synergy with dexamethasone[1].
References	[1]. Nooka AK, et al. Mechanism of Action and Novel IMiD-Based Compounds and Combinations in Multiple Myeloma. Cancer J. 2019 Jan/Feb;25(1):19-31.

Molecular Formula	C₃₂H₃₀FN₅O₄
Molecular Weight	567.61

Hazard Codes	Xi

MFCD32263041

DC Chemicals Limited
China
Product Name: CC-92480
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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