Azido-PEG2-propargyl

Modify Date: 2024-01-09 23:38:28

Azido-PEG2-propargyl Structure
Azido-PEG2-propargyl structure
Common Name Azido-PEG2-propargyl
CAS Number 1245006-63-6 Molecular Weight 169.18
Density N/A Boiling Point N/A
Molecular Formula C7H11N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-propargyl


Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG2-propargyl
Synonym More Synonyms

 Azido-PEG2-propargyl Biological Activity

Description Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1008.

 Chemical & Physical Properties

Molecular Formula C7H11N3O2
Molecular Weight 169.18

 Synonyms

MFCD24457814