DBCO-PEG2-acid

Modify Date: 2024-01-03 18:32:18

DBCO-PEG2-acid Structure
DBCO-PEG2-acid structure
Common Name DBCO-PEG2-acid
CAS Number 2304558-25-4 Molecular Weight 464.51
Density N/A Boiling Point N/A
Molecular Formula C26H28N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG2-acid


DBCO-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG2-acid

 DBCO-PEG2-acid Biological Activity

Description DBCO-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H28N2O6
Molecular Weight 464.51