(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine

Modify Date: 2025-09-23 08:12:38

(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine Structure
(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine structure
Common Name (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
CAS Number 2347517-69-3 Molecular Weight 750.91
Density N/A Boiling Point N/A
Molecular Formula C41H46N6O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine


(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia[1].

 Names

Name (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine

  Biological Activity

Description (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia[1].
Related Catalog
References

[1]. Method for dual-target construction of protac, and use thereof. WO2020119192A1.

 Chemical & Physical Properties

Molecular Formula C41H46N6O6S
Molecular Weight 750.91
InChIKey NQNKFJCCIWJMPC-LVNYTEOHSA-N
SMILES Cc1ncsc1-c1ccc(C(C)NC(=O)C2CC(O)CN2C(=O)C(NC(=O)CCC(=O)NC(c2cccnc2)c2cc3ccccc3o2)C(C)(C)C)cc1
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