BTK-IN-9

Modify Date: 2024-01-10 12:16:33

BTK-IN-9 Structure
BTK-IN-9 structure
Common Name BTK-IN-9
CAS Number 2361192-21-2 Molecular Weight 481.46
Density N/A Boiling Point N/A
Molecular Formula C25H19N7O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BTK-IN-9


BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells[1].

 Names

Name BTK-IN-9

 BTK-IN-9 Biological Activity

Description BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells[1].
Related Catalog
References

[1]. Ran F, et al. Design and synthesis of novel pyrazolopyrimidine-based derivatives as reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. Med Chem Res, 2022, 31, 594-604.

 Chemical & Physical Properties

Molecular Formula C25H19N7O4
Molecular Weight 481.46