Hyperforin dicyclohexylammonium salt

Modify Date: 2024-01-07 07:44:35

Hyperforin dicyclohexylammonium salt structure	Common Name	Hyperforin dicyclohexylammonium salt
	CAS Number	238074-03-8	Molecular Weight	718.10300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₇H₇₅NO₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS05, GHS07, GHS09	Signal Word	Danger

Use of Hyperforin dicyclohexylammonium salt

Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect[1][2].

Name	N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
Synonym	More Synonyms

Description	Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
In Vitro	Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) has a multi-directional mechanism of action. It blocks conductance of ligand-gated (GABA, NMDA, and AMPA receptors) and voltage-gated channels (Ca2+, K+, and Na+)[2].
References	[1]. Heiser JH, et al. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling. J Neurochem. 2013 Nov;127(3):303-13. [2]. Pochwat B, et al. Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice. Front Mol Neurosci. 2018 Dec 12;11:456.

Molecular Formula	C₄₇H₇₅NO₄
Molecular Weight	718.10300
Exact Mass	717.57000
PSA	83.47000
LogP	12.62200

Symbol	GHS05, GHS07, GHS09
Signal Word	Danger
Hazard Statements	H302-H314-H400
Precautionary Statements	P273-P280-P305 + P351 + P338-P310
RIDADR	UN 1759 8 / PGIII

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hyperforin dicyclohexylammonium salt

Hyp-DCHA Hyperforin-DCHA

Hyp-DCHA

Hyperforin-DCHA