Hyperforin dicyclohexylammonium salt

Modify Date: 2024-01-07 07:44:35

Hyperforin dicyclohexylammonium salt Structure
Hyperforin dicyclohexylammonium salt structure
Common Name Hyperforin dicyclohexylammonium salt
CAS Number 238074-03-8 Molecular Weight 718.10300
Density N/A Boiling Point N/A
Molecular Formula C47H75NO4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

 Use of Hyperforin dicyclohexylammonium salt


Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect[1][2].

 Names

Name N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
Synonym More Synonyms

 Hyperforin dicyclohexylammonium salt Biological Activity

Description Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect[1][2].
Related Catalog
In Vitro Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) has a multi-directional mechanism of action. It blocks conductance of ligand-gated (GABA, NMDA, and AMPA receptors) and voltage-gated channels (Ca2+, K+, and Na+)[2].
References

[1]. Heiser JH, et al. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling. J Neurochem. 2013 Nov;127(3):303-13.

[2]. Pochwat B, et al. Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice. Front Mol Neurosci. 2018 Dec 12;11:456.

 Chemical & Physical Properties

Molecular Formula C47H75NO4
Molecular Weight 718.10300
Exact Mass 717.57000
PSA 83.47000
LogP 12.62200

 Safety Information

Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger
Hazard Statements H302-H314-H400
Precautionary Statements P273-P280-P305 + P351 + P338-P310
RIDADR UN 1759 8 / PGIII

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 Synonyms

hyperforin dicyclohexylammonium salt
Hyp-DCHA Hyperforin-DCHA
Hyp-DCHA
Hyperforin-DCHA