Topoisomerase I inhibitor 6

Modify Date: 2025-08-27 12:27:09

Topoisomerase I inhibitor 6 Structure
Topoisomerase I inhibitor 6 structure
Common Name Topoisomerase I inhibitor 6
CAS Number 2393082-56-7 Molecular Weight 411.46
Density N/A Boiling Point N/A
Molecular Formula C23H21N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Topoisomerase I inhibitor 6


Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases[1].

 Names

Name Topoisomerase I inhibitor 6

 Topoisomerase I inhibitor 6 Biological Activity

Description Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases[1].
Related Catalog
References

[1]. Kundu B, et al. Development of a metabolically stable topoisomerase I poison as anticancer agent. Eur J Med Chem. 2020 Sep 15;202:112551. doi: 10.1016/j.ejmech.2020.112551.

 Chemical & Physical Properties

Molecular Formula C23H21N7O
Molecular Weight 411.46
InChIKey ZKIKODBQYDIGIR-UHFFFAOYSA-N
SMILES Nc1ccc(-c2ccc3ncc(-c4nnco4)c(NCCCn4ccnc4)c3c2)cc1
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