Meranzin

Modify Date: 2025-08-31 17:34:18

Meranzin Structure
Meranzin structure
Common Name Meranzin
CAS Number 23971-42-8 Molecular Weight 260.285
Density 1.2±0.1 g/cm3 Boiling Point 414.8±45.0 °C at 760 mmHg
Molecular Formula C15H16O4 Melting Point N/A
MSDS N/A Flash Point 185.3±28.8 °C

 Use of Meranzin


Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2].

 Names

Name 8-{[(2S)-3,3-Dimethyl-2-oxiranyl]methyl}-7-methoxy-2H-chromen-2-o ne
Synonym More Synonyms

 Meranzin Biological Activity

Description Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2].
Related Catalog
References

[1]. Lan Li, et al. Chaihu-Shugan-San and Absorbed Meranzin Hydrate Induce Anti-Atherosclerosis and Behavioral Improvements in High-Fat Diet ApoE -/- Mice via Anti-Inflammatory and BDNF-TrkB Pathway. Biomed Pharmacother. 2019 Jul;115:108893.

[2]. Rongwei Yan, et al. Preparative Isolation and Purification of Hainanmurpanin, Meranzin, and Phebalosin From Leaves of Murraya Exotica L. Using Supercritical Fluid Extraction Combined With Consecutive High-Speed Countercurrent Chromatography. J Sep Sci. 2018 May;41(9):2092-2101.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 414.8±45.0 °C at 760 mmHg
Molecular Formula C15H16O4
Molecular Weight 260.285
Flash Point 185.3±28.8 °C
Exact Mass 260.104858
PSA 51.97000
LogP 1.92
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.567

 Safety Information

Hazard Codes Xi

 Synonyms

pimelic acid monomethyl ester
8-{[(2S)-3,3-Dimethyl-2-oxiranyl]methyl}-7-methoxy-2H-chromen-2-one
6-methoxycarbonylhexanoic acid
methyl hydrogenpimelate
monomethyl heptanedioate
Heptanedioic acid,1-methyl ester
2H-1-Benzopyran-2-one, 8-[[(2S)-3,3-dimethyloxiranyl]methyl]-7-methoxy-
Heptanedioic acid,monomethyl ester
Methyl hydrogen heptane-1,7-dioate
Monomethyl pimelate
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