TRβ agonist 2

Modify Date: 2025-08-25 18:06:02

TRβ agonist 2 structure	Common Name	TRβ agonist 2
	CAS Number	2411099-30-2	Molecular Weight	369.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₇NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TRβ agonist 2

TRβ agonist 2 (Compound 1) is a potent agonist of TRβ. TRβ agonist 2 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 2 is a new potential TRβ-selective thyromimetics[1].

Name	TRβ agonist 2

Description	TRβ agonist 2 (Compound 1) is a potent agonist of TRβ. TRβ agonist 2 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 2 is a new potential TRβ-selective thyromimetics[1].
Related Catalog	Signaling Pathways >> Others >> Thyroid Hormone Receptor Research Areas >> Metabolic Disease
References	[1]. Runfola M, et al. Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis. Eur J Med Chem. 2020 Feb 15;188:112006.

Molecular Formula	C₂₂H₂₇NO₄
Molecular Weight	369.45
InChIKey	GZHDROJXCQEXMK-UHFFFAOYSA-N
SMILES	CC(=O)Nc1ccc(Cc2c(C)cc(OCC(=O)O)cc2C)cc1C(C)C

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