MPro Inhibitor 11b
Modify Date: 2024-01-09 08:20:22
MPro Inhibitor 11b structure
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Common Name | MPro Inhibitor 11b | ||
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| CAS Number | 2413716-71-7 | Molecular Weight | 464.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H25FN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MPro Inhibitor 11bSARS-CoV MPro-IN-1 is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. SARS-CoV MPro-IN-1 shows good anti-SARS-CoV-2-infection activity in cell culture with an EC50 of 0.33 μM. SARS-CoV MPro-IN-1 has the potential for COVID-19 research[1]. |
| Name | SARS-CoV MPro-IN-1 |
|---|
| Description | SARS-CoV MPro-IN-1 is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. SARS-CoV MPro-IN-1 shows good anti-SARS-CoV-2-infection activity in cell culture with an EC50 of 0.33 μM. SARS-CoV MPro-IN-1 has the potential for COVID-19 research[1]. |
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| Related Catalog | |
| In Vivo | SARS-CoV MPro-IN-1 (compound 11b) (5 mg/kg; intravenous drip administration) shows the t1/2 is <1.65 hours and the clearance rate is 20.6 mL/min/mg[1]. |
| References |
| Molecular Formula | C25H25FN4O4 |
|---|---|
| Molecular Weight | 464.49 |