A2A/A1 AR antagonist-1

Modify Date: 2024-01-12 11:21:38

A2A/A1 AR antagonist-1 Structure
A2A/A1 AR antagonist-1 structure
Common Name A2A/A1 AR antagonist-1
CAS Number 2445615-24-5 Molecular Weight 308.29
Density N/A Boiling Point N/A
Molecular Formula C15H12N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A2A/A1 AR antagonist-1


A2A/A1 AR antagonist-1 (compound 1a) is dual potent A2A/A1 AR antagonist with Kis of 5.58 and 24.2 nM, respectively. A2A/A1 AR antagonist-1 has the potential for the research of ischemic stroke[1].

 Names

Name A2A/A1 AR antagonist-1

 A2A/A1 AR antagonist-1 Biological Activity

Description A2A/A1 AR antagonist-1 (compound 1a) is dual potent A2A/A1 AR antagonist with Kis of 5.58 and 24.2 nM, respectively. A2A/A1 AR antagonist-1 has the potential for the research of ischemic stroke[1].
Related Catalog
References

[1]. Tang ML, et al. Discovery of Pyridone-Substituted Triazolopyrimidine Dual A2A/A1 AR Antagonists for the Treatment of Ischemic Stroke. ACS Med Chem Lett. 2022;13(3):436-442. Published 2022 Feb 21.

 Chemical & Physical Properties

Molecular Formula C15H12N6O2
Molecular Weight 308.29