VEGFR-2-IN-24
Modify Date: 2025-08-20 20:26:46
VEGFR-2-IN-24 structure
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Common Name | VEGFR-2-IN-24 | ||
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| CAS Number | 2455414-26-1 | Molecular Weight | 529.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H23N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VEGFR-2-IN-24VEGFR-2-IN-24 is a potent VEGFR-2 inhibitor with IC50 value of 0.22 µM. VEGFR-2-IN-24 can be used for tumor research[1]. |
| Name | VEGFR-2-IN-24 |
|---|
| Description | VEGFR-2-IN-24 is a potent VEGFR-2 inhibitor with IC50 value of 0.22 µM. VEGFR-2-IN-24 can be used for tumor research[1]. |
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| Related Catalog | |
| Target |
VEGFR2:0.22 μM (IC50) |
| In Vitro | VEGFR-2-IN-24 (Compound 8f) (0-1000 μM, 72 hours; human tumor cell lines) exerts the most potent antitumor activities against human cancer cell lines[1]. VEGFR-2-IN-24 (Compound 8f) (0-1000 μM, 72 hours; human tumor cell lines) displays the highest anticancer activities with IC50 values of 11.19, 8.99 and 7.10 μM for HepG2, HCT-116 and MCF-7 cell lines, respectively[1]. VEGFR-2-IN-24 (Compound 8f) (0-300 μg/mL, 5 min) remarkably exhibits VEGFR-2 inhibition with IC50 value of 0.22 µM[1]. Cell Cytotoxicity Assay[1] Cell Line: Hepatocellular carcinoma (HepG2), breast cancer (MCF-7) and colorectal carcinoma (HCT-116). Concentration: 0.1, 10, 100 and 1000 µM Incubation Time: 72 hours Result: Inhibited with IC50 values of 11.19, 8.99 and 7.10 μM for HePG-2, MCF-7 and HCT-116, respectively. |
| References |
| Molecular Formula | C28H23N3O6S |
|---|---|
| Molecular Weight | 529.56 |