VEGFR-2-IN-26

Modify Date: 2025-08-25 17:14:41

VEGFR-2-IN-26 Structure
VEGFR-2-IN-26 structure
Common Name VEGFR-2-IN-26
CAS Number 2439096-06-5 Molecular Weight 480.44
Density N/A Boiling Point N/A
Molecular Formula C24H19F3N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VEGFR-2-IN-26


VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].

 Names

Name VEGFR-2-IN-26

 VEGFR-2-IN-26 Biological Activity

Description VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].
Related Catalog
Target

VEGFR-2:15.5 nM (IC50)

References

[1]. Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961.

 Chemical & Physical Properties

Molecular Formula C24H19F3N6O2
Molecular Weight 480.44
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