TRi-1(TXNRD1 inhibitor 1)

Modify Date: 2024-01-08 11:58:46

TRi-1(TXNRD1 inhibitor 1) structure	Common Name	TRi-1(TXNRD1 inhibitor 1)
	CAS Number	246020-68-8	Molecular Weight	328.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₉ClN₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TRi-1(TXNRD1 inhibitor 1)

TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy[1].

Name	TRi-1

Description	TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 12 nM (TXNRD1)[1].
References	[1]. Stafford WC, et al. Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444.

Molecular Formula	C₁₂H₉ClN₂O₅S
Molecular Weight	328.73
Storage condition	2-8℃

DC Chemicals Limited
China
Product Name: TRi-1(TXNRD1 inhibitor 1)
Price: $550.0/100mg $950.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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