Aβ-IN-3

Modify Date: 2024-01-09 17:18:49

Aβ-IN-3 Structure
Aβ-IN-3 structure
Common Name Aβ-IN-3
CAS Number 2477606-87-2 Molecular Weight 621.72
Density N/A Boiling Point N/A
Molecular Formula C33H43N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aβ-IN-3


Aβ-IN-3 (compound 1) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-3 inhibits Aβ42 aggregation. However, Aβ-IN-3 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-3 can not change the aggregation state of Aβ42 into a nontoxic one[1].

 Names

Name Aβ-IN-3

 Aβ-IN-3 Biological Activity

Description Aβ-IN-3 (compound 1) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-3 inhibits Aβ42 aggregation. However, Aβ-IN-3 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-3 can not change the aggregation state of Aβ42 into a nontoxic one[1].
Related Catalog
References

[1]. Tanaka F, et al. Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein. Bioorg Med Chem. 2020 Sep 15;28(18):115676.

 Chemical & Physical Properties

Molecular Formula C33H43N5O7
Molecular Weight 621.72