JAK2-IN-9

Modify Date: 2025-09-10 21:46:56

JAK2-IN-9 structure	Common Name	JAK2-IN-9
	CAS Number	2568842-26-0	Molecular Weight	412.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₄N₆O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JAK2-IN-9

JAK2-IN-9 (Compound A8) is a selective JAK2 inhibitor (IC50: 5 nM). JAK2-IN-9 inhibits the phosphorylation of JAK2, STAT3, and STAT5. JAK2-IN-9 has metabolic stabilities. JAK2-IN-9 induces apoptosis. JAK2-IN-9 can be used for research of myeloproliferative neoplasms (MPNs)[1].

Name	JAK2-IN-9

Description	JAK2-IN-9 (Compound A8) is a selective JAK2 inhibitor (IC50: 5 nM). JAK2-IN-9 inhibits the phosphorylation of JAK2, STAT3, and STAT5. JAK2-IN-9 has metabolic stabilities. JAK2-IN-9 induces apoptosis. JAK2-IN-9 can be used for research of myeloproliferative neoplasms (MPNs)[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	JAK2
References	[1]. Tian Y, et al Discovery of N-(4-(Aminomethyl)phenyl)-5-methylpyrimidin-2-amine Derivatives as Potent and Selective JAK2 Inhibitors. ACS Med Chem Lett. 2023 Aug 1;14(8):1113-1121.

Molecular Formula	C₂₀H₂₄N₆O₂S
Molecular Weight	412.51
InChIKey	TWDAYUKEAHMUJM-UHFFFAOYSA-N
SMILES	C=CS(=O)(=O)NCc1ccc(Nc2ncc(C)c(-c3cnn(C(C)C)c3)n2)cc1

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JAK2-IN-9

Use of JAK2-IN-9

Names

JAK2-IN-9 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.